Lecture 2: Introduction to Hemostasis

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1.
Inherited bleeding disorder associated with a deficiency of Factor VIII.
2.
Inherited bleeding disorder associated with a deficiency of Factor IX.
3.
vWF, collagen, and GP Ib/IX/V play a major role in platelet __________.
4.
Fibrinogen, GP IIb/IIIa, and calcium play a major role in platelet _________.
5.
Quantitative platelet defect seen in young children following a viral infection or recent immunizations.
6.
A consumptive microangiopathy that results in abnormal activation and consumption of clotting factors and platelets.
7.
A consumptive microangiopathy associated with an autoantibody to ADAMTS-13 and neurological problems.
8.
A consumptive microangiopathy associated with E. coli O157:H7 and renal failure
9.
Coagulation factor pathway that includes Tissue Factor and FVII.
10.
Coagulation factor pathway that includes Factors VIII, IX, XI, XII, PK, and HMWK.
11.
Coagulation factory pathway that includes Factors I, II, V, and X.
12.
Medical terminology for a nosebleed.
13.
Term for pinpoint hemorrhages in the skin.
14.
Enzyme responsible for converting fibrinogen to fibrin
15.
Anti-platelet medication that interferes with cyclooxygenase enzymes and inhibits thromboxane A2 synthesis.
16.
The enzyme that digests fibrin clots during fibrinolysis.
17.
RBC morphology seen in the peripheral blood of patients with TTP, DIC, and HUS.
18.
Bernard-Soulier syndrome is associated with thrombocytopenia and ___________ platelets.
19.
___________ time is used to monitor the extrinsic pathway and common pathway of coagulation and oral anticoagulant therapy
20.
________________ used to monitor the intrinsic and common pathway of coagulation and unfractionated heparin therapy
21.
_____________ time detects qualitative platelet defects
22.
Medical terminology for heavy and/or prolonged bleeding during menstruation.
23.
Medical terminology for bleeding into the joints.
24.
Hemorrhages in skin more than 1 cm in diameter.
25.
Medical terminology for vomiting blood.