How Are New Vaccines/Drugs Developed Word Search

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A federal agency which is a source of reliable, scientific based information for the general public
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Made from living organisms: They are produced from a variety of biological sources, such as proteins, antibodies, hormones, and nucleic acids, and can be isolated from natural sources like microorganisms, plants, animals, and humans.
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study conducted at more than one hospital, clinic, or research institution, following a single, common protocol and data collection plan
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neither participants or researchers know who is getting the treatment vs who is getting the placebo
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a study where participants, researchers, AND data analyzers all don’t know
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This enzyme has only one job- to activate a harmless prodrug into a toxic chemotherapy drug, but only within the tumor.
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bacteria killing mechanism including hypoxia tolerance, chemotaxis, motility genes.
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bacteria killing mechanism that involved apoptosis + pyroptosis.
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fully inactivated bacteria composed of bacterial shells with pores, with a partial or complete release of their cellular components.
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acronym for virus like particles
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Attenuated listeria engineered to be antibiotic-sensitive. Delivers reporter or therapeutic genes inside tumors.
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The most effective method to create non-denatured bacterial ghosts that uses the phage ΦX174 LyE protein is called________
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_________outperform naked DNA vaccines, producing stronger humoral immunity, T-cell activation, lymphocyte proliferation, and Th1 polarization.
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Viruses that infect bacteria are called_______
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____and ______independently discovered bacteriophages in 1915 and 1917 respectively
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______and other small molecule antimicrobials entered the scene in 1928, this one antimicrobial specifically was discovered by Alexander Fleming.
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________ in phage therapy is a phrase that describes how the US is turning back to these past methods and trying to figure out not only how we can specifically find phages to target certain bacteria, but how we can use phage in a more widespread way.
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Physicians can submit requests to use phage for ______________________ when the patient’s case meets a list of criteria.
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There is an emerging approach that uses ________to deliver radiopharmaceuticals directly into tumors.The bacteria act as a targeting mechanism, bringing radioactive ligands to cancer cells and delivering highly localized radiation.
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Among all bacterial species tested, _________________________ has become the most popular because of how reliably it targets and grows inside tumors.
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________________________genes are good because it allows for the transfer of plasmids instead of remaining in a vacuole, the immune response in general is host derived in the response of a foreign object being present BUT it then isolates the DNA.