All About Antibodies

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1.
AKA Immunoglobulin, Glycoprotein produced by B lymphocytes and plasma cells in response to foreign substance exposure.
2.
Is One of the polypeptide units that make up an immunoglobulin molecule.
3.
Is a small chain in an immunoglobulin molecule that is bound to the larger chain by disulfide bonds.
4.
Is one or two types of light chains present in ~2/3 of immunoglobulins.
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Is one or two types of light chains present in ~1/3 immunoglobulins.
6.
Is a amino-terminal region of an antibody that has a unique amino acid sequence and is responsible for the specificity of the antibody.
7.
Is a carboxy-terminal segment of an antibody molecule that consists of a polypeptide sequence found in all chains of that type.
8.
Is a flexible portion of the heavy chain of an immunoglobulin molecule that is located between the 1st and 2nd constant regions that allows the molecule to bend and antigen-binding sites to operate independently.
9.
Is a glycoprotein that links immunoglobulin monomers together this would only be found in IgM and IgA.
10.
Is a fragment of an immunoglobulin molecule obtained by papain cleavage that consists of a light chain and 1/2 of a heavy chain held together by disulfide bounding.
11.
Is a fragment of an immunoglobulin molecule obtained by papain cleavage that consists of the carboxy-terminal halves of 2 heavy chains that are held together by disulfide bonds.
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Is a very specific antibody derived from a single antibody producing cell that has been cloned or duplicated.
13.
Is a two-dimensional structure consisting of 2 heavy chains and 2 light chains.
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Immunoglobulin G are the most abundant type of antibody in the blood, produced by the immune system to fight off bacterial and viral infections.
15.
Immunoglobulin M is the largest antibody in the human immune system and serves as the "first responder" to new infections.
16.
Immunoglobulin A is an antibody that plays a critical role in mucosal immunity, acting as a primary line of defense at the body's points of entry.
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Immunoglobulin D is a monomeric antibody that accounts for less than 1% of the total immunoglobulins in human serum.
18.
Immunoglobulin E is the least abundant antibody in the bloodstream but one of the most powerful, playing a central role in allergic reactions and defense against parasitic infections.